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Jinek
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Publications of the Jinek Group
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Publications
2019
Jinek, Martin (2019).
Uncut but primed for change.
The CRISPR journal, 2(6):352-354.
Allain, Frédéric H-T; Jinek, Martin (2019).
Editorial overview: Protein-nucleic acid interactions - cryo-EM, what else?.
Current Opinion in Structural Biology, 59:vi-viii.
Kumar, Ananthanarayanan; Clerici, Marcello; Muckenfuss, Lena M; Passmore, Lori A; Jinek, Martin (2019).
Mechanistic insights into mRNA 3'-end processing.
Current Opinion in Structural Biology, 59:143-150.
Dumeau, Charles-Etienne; Monfort, Asun; Kissling, Lucas; Swarts, Daan C; Jinek, Martin; Wutz, Anton (2019).
Introducing gene deletions by mouse zygote electroporation of Cas12a/Cpf1.
Transgenic research, 28(5-6):525-535.
Boneberg, Franziska M; Brandmann, Tobias; Kobel, Lena; van den Heuvel, Jasmin; Bargsten, Katja; Bammert, Lukas; Kutay, Ulrike; Jinek, Martin (2019).
Corrigendum: Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
RNA, 25(11):1576.
Hegge, Jorrit W; Swarts, Daan C; Chandradoss, Stanley D; Cui, Tao Ju; Kneppers, Jeroen; Jinek, Martin; Joo, Chirlmin; van der Oost, John (2019).
DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.
Nucleic Acids Research, 47(11):5809-5821.
Boneberg, Franziska M; Brandmann, Tobias; Kobel, Lena; van den Heuvel, Jasmin; Bargsten, Katja; Bammert, Lukas; Kutay, Ulrike; Jinek, Martin (2019).
Molecular mechanism of the RNA helicase DHX37 and its activation by UTP14A in ribosome biogenesis.
RNA, 25(6):685-701.
Ricci, Clarisse G; Chen, Janice S; Miao, Yinglong; Jinek, Martin; Doudna, Jennifer A; McCammon, J Andrew; Palermo, Giulia (2019).
Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics.
ACS Central Science, 5(4):651-662.
Swarts, Daan C; Jinek, Martin (2019).
Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a.
Molecular Cell, 73(3):589-600.e4.
Kroupova, Alena; Ivaşcu, Anastasia; Reimão-Pinto, Madalena M; Ameres, Stefan L; Jinek, Martin (2019).
Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Research, 47(2):1030-1042.
Savić, Nataša; Ringnalda, Femke Cas; Berk, Christian; Bargsten, Katja; Hall, Jonathan; Jinek, Martin; Schwank, Gerald (2019).
In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells..
Bio-protocol, 9(1):1-48.
2018
Nishimura, Tamiko; Fakim, Hana; Brandmann, Tobias; Youn, Ji-Young; Gingras, Anne-Claude; Jinek, Martin; Fabian, Marc R (2018).
Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.
Nucleic Acids Research, 46(22):12008-12021.
Savic, Natasa; Ringnalda, Femke C A S; Lindsay, Helen; Berk, Christian; Bargsten, Katja; Li, Yizhou; Neri, Dario; Robinson, Mark D; Ciaudo, Constance; Hall, Jonathan; Jinek, Martin; Schwank, Gerald (2018).
Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.
eLife, 7:33761.
Swarts, Daan C; Jinek, Martin (2018).
Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing.
Wiley Interdisciplinary Reviews. RNA, 9:e1481.
Brandmann, Tobias; Fakim, Hana; Padamsi, Zoya; Youn, Ji-Young; Gingras, Anne-Claude; Fabian, Marc R; Jinek, Martin (2018).
Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.
The EMBO Journal, 37(7):e97869.
Clerici, Marcello; Faini, Marco; Muckenfuss, Lena M; Aebersold, Ruedi; Jinek, Martin (2018).
Author Correction: Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
Nature Structural & Molecular Biology, 25(4):355.
Clerici, Marcello; Faini, Marco; Muckenfuss, Lena M; Aebersold, Ruedi; Jinek, Martin (2018).
Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
Nature Structural & Molecular Biology, 25(2):135-138.
Vlot, Marnix; Houkes, Joep; Lochs, Silke J A; Swarts, Daan C; Zheng, Peiyuan; Kunne, Tim; Mohanraju, Prarthana; Anders, Carolin; Jinek, Martin; van der Oost, John; Dickman, Mark J; Brouns, Stan J J (2018).
Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR-Cas effector complexes.
Nucleic Acids Research, 46(2):873-885.
Palermo, Giulia; Chen, Janice S; Ricci, Clarisse G; Rivalta, Ivan; Jinek, Martin; Batista, Victor S; Doudna, Jennifer A; McCammon, J Andrew (2018).
Key role of the REC lobe during CRISPR-Cas9 activation by 'sensing', 'regulating', and 'locking' the catalytic HNH domain.
Quarterly reviews of biophysics, 51:e91.
2017
Clerici, Marcello; Faini, Marco; Aebersold, Ruedi; Jinek, Martin (2017).
Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex.
eLife, 6:e33111.
Palermo, Giulia; Ricci, Clarisse G; Fernando, Amendra; Basak, Rajshekhar; Jinek, Martin; Rivalta, Ivan; Batista, Victor S; McCammon, J Andrew (2017).
Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9.
Journal of the American Chemical Society, 139(45):16028-16031.
Garcia-Doval, Carmela; Jinek, Martin (2017).
Molecular architectures and mechanisms of Class 2 CRISPR-associated nucleases.
Current Opinion in Structural Biology, 47:157-166.
Niewoehner, Ole; Jinek, Martin (2017).
Specialized weaponry: how a type III-A CRISPR-cas system excels at combating phages.
Cell Host & Microbe, 22(3):258-259.
Niewoehner, Ole; Garcia-Doval, Carmela; Rostøl, Jakob T; Berk, Christian; Schwede, Frank; Bigler, Laurent; Hall, Jonathan; Marraffini, Luciano A; Jinek, Martin (2017).
Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers.
Nature, 548(7669):543-548.
Palermo, Giulia; Miao, Yinglong; Walker, Ross C; Jinek, Martin; McCammon, J Andrew (2017).
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations.
Proceedings of the National Academy of Sciences of the United States of America, 114(28):7260-7265.
Swarts, Daan C; van der Oost, John; Jinek, Martin (2017).
Structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a.
Molecular Cell, 66(2):221-233.e4.
2016
Reimão-Pinto, Madalena M; Manzenreither, Raphael A; Burkard, Thomas R; Sledz, Pawel; Jinek, Martin; Mechtler, Karl; Ameres, Stefan L (2016).
Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.
The EMBO Journal, 35(22):2417-2434.
Lindsay, Helen; Burger, Alexa; Biyong, Berthin; Felker, Anastasia; Hess, Christopher; Zaugg, Jonas; Chiavacci, Elena; Anders, Carolin; Jinek, Martin; Mosimann, Christian; Robinson, Mark D (2016).
CrispRVariants charts the mutation spectrum of genome engineering experiments.
Nature Biotechnology, 34(7):701-702.
Burger, Alexa; Lindsay, Helen; Felker, Anastasia; Hess, Christopher; Anders, Carolin; Chiavacci, Elena; Zaugg, Jonas; Weber, Lukas M; Catena, Raul; Jinek, Martin; Robinson, Mark D; Mosimann, Christian (2016).
Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes.
Development, 143(11):2025-2037.
Anders, Carolin; Bargsten, Katja; Jinek, Martin (2016).
Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Molecular Cell, 61(6):895-902.
Olieric, Vincent; Weinert, Tobias; Finke, Aaron D; Anders, Carolin; Li, Dianfan; Olieric, Natacha; Borca, Camelia N; Steinmetz, Michel O; Caffrey, Martin; Jinek, Martin; Wang, Meitian (2016).
Data-collection strategy for challenging native SAD phasing.
Acta Crystallographica. Section D: Structural Biology, 72(Pt 3):421-429.
Niewoehner, Ole; Jinek, Martin (2016).
Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6.
RNA, 22(3):318-329.
Palermo, Giulia; Miao, Yinglong; Walker, Ross C; Jinek, Martin; McCammon, J Andrew (2016).
Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.
ACS Central Science, 2(10):756-763.
Śledź, Paweł; Jinek, Martin (2016).
Structural insights into the molecular mechanism of the m(6)A writer complex.
eLife, 5:1-16.
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