Publications of the Plückthun Group

ZORA Publication List

Publications

• 2018

  • Vigano, M Alessandra; Bieli, Dimitri; Schaefer, Jonas V; Jakob, Roman P; Matsuda, Shinya; Maier, Timm; Plückthun, Andreas; Affolter, Markus (2018). Correction: DARPins recognizing mTFP1 as novel reagents for and protein manipulations (doi:10.1242/bio.036749). Biology Open, 7(12):1.
  • Ehrenmann, Janosch; Schöppe, Jendrik; Klenk, Christoph; Rappas, Mathieu; Kummer, Lutz; Doré, Andrew S; Plückthun, Andreas (2018). High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist. Nature Structural & Molecular Biology, 25(12):1086-1092.
  • Vigano, M Alessandra; Bieli, Dimitri; Schaefer, Jonas V; Jakob, Roman P; Matsuda, Shinya; Maier, Timm; Plückthun, Andreas; Affolter, Markus (2018). DARPins recognize mTFP1 as novel reagents for and protein manipulations. Biology Open, 7(11):036749.
  • ElGamacy, Mohammad; Coles, Murray; Ernst, Patrick; Zhu, Hongbo; Hartmann, Marcus D; Plückthun, Andreas; Lupas, Andrei N (2018). An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture. ACS Synthetic Biology, 7(9):2226-2235.
  • Hartmann, Jessica; Münch, Robert C; Freiling, Ruth-Therese; Schneider, Irene C; Dreier, Birgit; Samukange, Washington; Koch, Joachim; Seeger, Markus A; Plückthun, Andreas; Buchholz, Christian J (2018). A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors. Molecular Therapy - Methods & Clinical Development, 10:128-143.
  • Mikula, Kornelia M; Krumwiede, Luisa; Plückthun, Andreas; Iwaï, Hideo (2018). Segmental isotopic labeling by asparaginyl endopeptidase-mediated protein ligation. Journal of Biomolecular NMR, 71(4):225-235.
  • Wu, Yufan; Honegger, Annemarie; Batyuk, Alexander; Mittl, Peer R E; Plückthun, Andreas (2018). Structural Basis for the Selective Inhibition of c-Jun N-Terminal Kinase 1 Determined by Rigid DARPin-DARPin Fusions. Journal of Molecular Biology, 430(14):2128-2138.
  • Yen, Hsin-Yung; Hoi, Kin Kuan; Liko, Idlir; Hedger, George; Horrell, Michael R; Song, Wanling; Wu, Di; Heine, Philipp; Warne, Tony; Lee, Yang; Carpenter, Byron; Plückthun, Andreas; Tate, Christopher G; Sansom, Mark S P; Robinson, Carol V (2018). PtdIns(4,5)P stabilizes active states of GPCRs and enhances selectivity of G-protein coupling. Nature, 559(7714):423-427.
  • Radom, Filip; Plückthun, Andreas; Paci, Emanuele (2018). Assessment of ab initio models of protein complexes by molecular dynamics. PLoS Computational Biology, 14(6):e1006182.
  • Schaefer, Jonas V; Sedlák, Erik; Kast, Florian; Nemergut, Michal; Plückthun, Andreas (2018). Modification of the kinetic stability of immunoglobulin G by solvent additives. mAbs, 10(4):607-623.
  • Yong, Kelvin J; Vaid, Tasneem M; Shilling, Patrick J; Wu, Feng-Jie; Williams, Lisa M; Deluigi, Mattia; Plückthun, Andreas; Bathgate, Ross A D; Gooley, Paul R; Scott, Daniel J (2018). Determinants of Ligand Subtype-Selectivity at α-Adrenoceptor Revealed Using Saturation Transfer Difference (STD) NMR. ACS Chemical Biology, 13(4):1090-1102.
  • Stichling, Nicole; Suomalainen, Maarit; Flatt, Justin W; Schmid, Markus; Pacesa, Martin; Hemmi, Silvio; Jungraithmayr, Wolfgang; Maler, Mareike D; Freudenberg, Marina A; Plückthun, Andreas; May, Tobias; Köster, Mario; Fejer, György; Greber, Urs F (2018). Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor. PLoS Pathogens, 14(3):e1006914.
  • Hansen, Simon; Ernst, Patrick; König, Sebastian L B; Reichen, Christian; Ewald, Christina; Nettels, Daniel; Mittl, Peer R E; Schuler, Benjamin; Plückthun, Andreas (2018). Curvature of designed armadillo repeat proteins allows modular peptide binding. Journal of Structural Biology, 201(2):108-117.
  • Schmid, Markus; Ernst, Patrick; Honegger, Annemarie; Suomalainen, Maarit; Zimmermann, Martina; Braun, Lukas; Stauffer, Sarah; Thom, Cristian; Dreier, Birgit; Eibauer, Matthias; Kipar, Anja; Vogel, Viola; Greber, Urs F; Medalia, Ohad; Plückthun, Andreas (2018). Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nature Communications, 9(1):450.
  • Michel, Erich; Plückthun, Andreas; Zerbe, Oliver (2018). Peptide-guided assembly of repeat protein fragments. Angewandte Chemie Internationale Edition, 57(17):4576-4579.

• 2017

  • Hansen, Simon; Stüber, Jakob C; Ernst, Patrick; Koch, Alexander; Bojar, Daniel; Batyuk, Alexander; Plückthun, Andreas (2017). Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity. Scientific Reports, 7(1):16292.
  • Nemergut, Michal; Žoldák, Gabriel; Schaefer, Jonas V; Kast, Florian; Miškovský, Pavol; Plückthun, Andreas; Sedlák, Erik (2017). Analysis of IgG kinetic stability by differential scanning calorimetry, probe fluorescence and light scattering. Protein Science, 26(11):2229-2239.
  • Verdurmen, Wouter P R; Mazlami, Marigona; Plückthun, Andreas (2017). A quantitative comparison of cytosolic delivery via different protein uptake systems. Scientific Reports, 7(1):13194.
  • Hansen, Simon; Kiefer, Jonathan D; Madhurantakam, Chaithanya; Mittl, Peer R E; Plückthun, Andreas (2017). Structures of designed armadillo repeat proteins binding to peptides fused to globular domains. Protein Science, 26(10):1942-1952.
  • Wu, Yufan; Batyuk, Alexander; Honegger, Annemarie; Brandl, Fabian; Mittl, Peer R E; Plückthun, Andreas (2017). Rigidly connected multispecific artificial binders with adjustable geometries. Scientific Reports, 7(1):11217.
  • Jost, Christian; Stüber, Jakob C; Honegger, Annemarie; Wu, Yufan; Batyuk, Alexander; Plückthun, Andreas (2017). Rigidity of the extracellular part of HER2: evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions. Protein Science, 26(9):1796-1806.
  • Afroz, Tariq; Hock, Eva-Maria; Ernst, Patrick; Foglieni, Chiara; Jambeau, Melanie; Gilhespy, Larissa A B; Laferriere, Florent; Maniecka, Zuzanna; Plückthun, Andreas; Mittl, Peer; Paganetti, Paolo; Allain, Frédéric H T; Polymenidou, Magdalini (2017). Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation. Nature Communications, 8:45.
  • Parren, Paul W H I; Carter, Paul J; Plückthun, Andreas (2017). Changes to International Nonproprietary Names for antibody therapeutics 2017 and beyond: of mice, men and more. mAbs, 9(6):898-906.
  • Ranganathan, Anirudh; Heine, Philipp; Rudling, Axel; Plückthun, Andreas; Kummer, Lutz; Carlsson, Jens (2017). Ligand discovery for a peptide-binding GPCR by Structure-based screening of fragment- and lead-like chemical libraries. ACS Chemical Biology, 12(3):735-745.
  • Anders, Ulrike; Schaefer, Jonas V; Hibti, Fatima-Ezzahra; Frydman, Chiraz; Suckau, Detlev; Plückthun, Andreas; Zenobi, Renato (2017). SPRi-MALDI MS: characterization and identification of a kinase from cell lysate by specific interaction with different designed ankyrin repeat proteins. Analytical and Bioanalytical Chemistry, 409(7):1827-1836.
  • Syafrizayanti; Lueong, Smiths S; Di, Cuixia; Schaefer, Jonas V; Plückthun, Andreas; Hoheisel, Jörg D (2017). Personalised proteome analysis by means of protein microarrays made from individual patient samples. Scientific Reports, 7:39756.
  • Ernst, Patrick; Plückthun, Andreas (2017). Advances in the design and engineering of peptide-binding repeat proteins. Biological Chemistry, 398(1):23-29.
  • Nasr, Mahmoud L; Baptista, Diego; Strauss, Mike; Sun, Zhen-Yu J; Grigoriu, Simina; Huser, Sonja; Plückthun, Andreas; Hagn, Franz; Walz, Thomas; Hogle, James M; Wagner, Gerhard (2017). Covalently circularized nanodiscs for studying membrane proteins and viral entry. Nature Methods, 14(1):49-52.
  • Huber, Sylwia; Casagrande, Fabio; Hug, Melanie N; Wang, Lisha; Heine, Philipp; Kummer, Lutz; Plückthun, Andreas; Hennig, Michael (2017). SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands. PLoS ONE, 12(5):e0175842.
  • Verdurmen, Wouter P R; Mazlami, Marigona; Plückthun, Andreas (2017). A Biotin Ligase-Based Assay for the Quantification of the Cytosolic Delivery of Therapeutic Proteins. Methods in Molecular Biology, 1575:223-236.

Pagination